SLU-PP-332 is a synthetic small-molecule compound developed at St. Louis University that acts as a pan-agonist of Estrogen-Related Receptors (ERRα, ERRβ, ERRγ). ERRs are orphan nuclear receptors that regulate mitochondrial biogenesis, oxidative metabolism, and fatty acid oxidation. In 2024, published research in Nature Communications described SLU-PP-332 as an 'exercise mimetic' — activating the same transcriptional programmes as aerobic exercise in rodent cardiac, skeletal muscle, and adipose tissue models. Supplied at ≥99% HPLC purity.
Add 1 mL DMSO or ethanol for initial dissolution, then dilute to desired working concentration in aqueous buffer. SLU-PP-332 has limited water solubility and requires an organic co-solvent.
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Store lyophilised at −20 °C, desiccated. Reconstituted in DMSO: −20 °C, stable for 6 months.
Every NewChem batch of SLU-PP-332 is independently tested prior to dispatch. Your COA documents HPLC purity (≥99%), identity confirmation via mass spectrometry, endotoxin screening, and a unique batch ID for full traceability. Sample COAs are available on request before purchase.
For a detailed step-by-step reconstitution guide for SLU-PP-332, including BAC water measurements, syringe unit conversions, and storage protocols, see our dedicated guide:
