MOTS-C (Mitochondrial Open reading frame of the 12S rRNA-c) is a 16-amino-acid mitochondrial-derived peptide encoded in the 12S ribosomal RNA gene of the mitochondrial genome. First characterised in 2015, it is studied for its role in metabolic regulation, insulin sensitivity, exercise physiology, and ageing. Published research has described MOTS-C as acting as a mitohormone — a signal transmitted from the mitochondria to the nucleus in response to metabolic stress.
Add 2 mL bacteriostatic water for 5,000 mcg/mL. MOTS-C dissolves readily at room temperature.
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Store lyophilised at −80 °C for long-term stability. Short-term storage at −20 °C acceptable. Reconstituted: 4 °C, use within 14 days.
Every NewChem batch of MOTS-C is independently tested prior to dispatch. Your COA documents HPLC purity (≥99%), identity confirmation via mass spectrometry, endotoxin screening, and a unique batch ID for full traceability. Sample COAs are available on request before purchase.
For a detailed step-by-step reconstitution guide for MOTS-C, including BAC water measurements, syringe unit conversions, and storage protocols, see our dedicated guide:
